Synthetic communications

A Convenient and Effective Method for Synthesizing β??Amino?螃?, β??Unsaturated Esters and Ketones

Y Gao, Q Zhang, J Xu

Index: Gao, Yuanhe; Zhang, Qihan; Xu, Jiaxi Synthetic Communications, 2004 , vol. 34, # 5 p. 909 - 916

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Citation Number: 61

Abstract

View all references In this method amines can be applied in aqueous solution and the use of solvents for removal of water is avoided. Due to the unavailability of montmorillonite K??10 in our hands we rationalized that silica gel having weak acidity would be suitable replacement as solid support for the reaction. Firstly, we found that an almost quantitative yield was obtained in reactions of acetoacetone and ethyl acetoacetate with ammonia by using silica gel. ...