Efficient regioselective functionalizations of cyclodextrins carried out under microwaves or power ultrasound

…, B Robaldo, N Belliardi, L Jicsinszky, G Cravotto

Index: Martina, Katia; Trotta, Francesco; Robaldo, Bruna; Belliardi, Nikka; Jicsinszky, Laszlo; Cravotto, Giancarlo Tetrahedron Letters, 2007 , vol. 48, # 52 p. 9185 - 9189

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Citation Number: 24

Abstract

Regioselective syntheses of differently functionalized cyclodextrins (CDs) were efficiently carried out under ultrasound or microwave irradiation. 6I-Deoxy-6I-thio-β-CD, 6I-deoxy-6I- formyl-β-CD, and 6A, 6D-dideoxy-6A, 6D-dithio-β-CD were prepared under microwave irradiation. A new rapid and efficient ultrasound-assisted protocol is described for the synthesis of 3I-azido-3I-deoxy-α,-β, and-γ-CD by selective tosylation followed by azide ...