Journal of medicinal chemistry

The Synthesis and Pharmacology of 131I-Labeled 1, 10-Bis (trimethylammonium)-5-chloro-6-iodo-5-decene Dihalide and Related Neuromuscular Blocking Agents

OA Nedergaard, DB Taylor

Index: Nedergaard,O.A.; Taylor,D.B. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 231 - 235

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Citation Number: 1

Abstract

Method B is identical with method A except that chloroform is used as the reaction solvent instead of absolute ethanol. Method C.-A mixture of 0.10 mole of orthoester, 0.10 mole of P- aminoethylhydrazirie, and 50 ml of ethyl acetate was refluxed for 20 hr and then distilled in z) acuo. Method D is identical with method C except that CHC13 is used as the reaction solvent, instead of ethyl acetate. Method E is the same as method C except that absolute ...