Tetrahedron letters

Indium triflate: a mild and efficient Lewis acid catalyst for O–H insertion reactions of α-diazo ketones

S Muthusamy, SA Babu, C Gunanathan

Index: Muthusamy, Sengodagounder; Babu, Srinivasarao Arulananda; Gunanathan, Chidambaram Tetrahedron Letters, 2002 , vol. 43, # 17 p. 3133 - 3136

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Citation Number: 31

Abstract

Facile O–H insertion reactions of α-diazo ketones with aliphatic/aromatic alcohols or benzenethiol have been developed in the presence of indium triflate as a catalyst. These reactions provided good yields of α-alkoxy ketones. A comparative study with other Lewis acids establishes the reactivity of indium triflate in O–H insertion reactions of α-diazo ketones.

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