Sarcosine based indandione hGlyT1 inhibitors

…, SR Fletcher, IT Huscroft, G Pillai, P Raubo…

Index: Thomson, Christopher G.; Duncan, Karen; Fletcher, Stephen R.; Huscroft, Ian T.; Pillai, Gopalan; Raubo, Piotr; Smith, Alison J.; Stead, Darren Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1388 - 1391

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Citation Number: 13

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of sarcosine based indandione hGlyT1 inhibitors has been developed. Optimization of substitution around the indandione and sarcosine moieties has led to highly potent inhibitors at hGlyT1, which show selectivity over a number of other receptors. ... A series of indandione sarcosine ...