A convenient synthesis of hetarylethynyl ketones from hetarylcarbaldehydes and acetylene

…, LN Sobenina, AI Mikhaleva, BA Trofimov

Index: Tomilin; Petrova; Sobenina; Mikhaleva; Trofimov Chemistry of Heterocyclic Compounds, 2013 , vol. 49, # 2 p. 341 - 344 Khim. Geterotsikl. Soedin., 2013 , vol. 49, # 2 p. 341 - 344,4

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Citation Number: 3

Abstract

Interest in α, β-acetylenic ketones is mainly due to the fact that the conjugated system of a triple bond and a carbonyl group is present in many natural compounds having biochemical activity [1]. α, β-Acetylenic ketones are often used for the synthesis [1, 2] and functionalization [3, 4] of various aromatic and heterocyclic compounds. Thus, a recently found palladium-free cross coupling of α, β-acetylenic ketones with pyrroles and indoles ...