Pentenolide Analogues of Antifungal Butenolides: Strategies Towards 3, 6-Disubstituted Pyranones and Unexpected Loss of Biological Effect

I Šnajdr, J Pavlík, R Schiller, J Kuneš…

Index: Snajdr, Ivan; Pavlik, Jan; Schiller, Radan; Kunes, Jiri; Pour, Milan Collection of Czechoslovak Chemical Communications, 2007 , vol. 72, # 11 p. 1472 - 1498

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Citation Number: 4

Abstract

Abstract Pentenolide analogues of antifungal 3, 5-disubstituted butenolides were prepared by oxidative cyclization of 2-(substituted aryl) hex-5-enoic acids as the key step. Given the limitations of the methodology, another approach to the title compounds based on the Pd- ...