Palladium-Catalyzed cross-Benzannulation of Aminoenynes with Diynes. Highly Regioselective Synthesis of Polysubstituted Anilines

S Saito, N Uchiyama, V Gevorgyan…

Index: Saito, Shinichi; Uchiyama, Naoyuki; Gevorgyan, Vladimir; Yamamoto, Yoshinori Journal of Organic Chemistry, 2000 , vol. 65, # 14 p. 4338 - 4341

Full Text: HTML

Citation Number: 28

Abstract

Polysubstituted anilines were prepared by the palladium-catalyzed cross-benzannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proceeded in a highly regioselective manner under mild conditions, and the anilines were obtained as single regioisomers. Our method complements the well-known precedures for the preparation of polysubstituted anilines which are widely used in organic synthesis.

Related Articles:

Synthetic elaboration of the side chain of (R)-2, 2-dimethyl-3-(tert-butoxycarbonyl)-4-ethynyloxazolidine: a new regio-and stereoselective strategy to δ-functionalized β …

[Reginato, Gianna; Mordini, Alessandro; Caracciolo, Massimo Journal of Organic Chemistry, 1997 , vol. 62, # 18 p. 6187 - 6192]

Synthetic elaboration of the side chain of (R)-2, 2-dimethyl-3-(tert-butoxycarbonyl)-4-ethynyloxazolidine: a new regio-and stereoselective strategy to δ-functionalized β …

[Reginato, Gianna; Mordini, Alessandro; Caracciolo, Massimo Journal of Organic Chemistry, 1997 , vol. 62, # 18 p. 6187 - 6192]

Synthesis of new chiral vinyl halides from L-serinal

[Branquet, Eric; Meffre, Patrick; Durand, Philippe; Le Goffic, Francois Synthetic Communications, 1998 , vol. 28, # 4 p. 613 - 622]

Synthesis of new chiral vinyl halides from L-serinal

[Branquet, Eric; Meffre, Patrick; Durand, Philippe; Le Goffic, Francois Synthetic Communications, 1998 , vol. 28, # 4 p. 613 - 622]

Synthetic elaboration of the side chain of (R)-2, 2-dimethyl-3-(tert-butoxycarbonyl)-4-ethynyloxazolidine: a new regio-and stereoselective strategy to δ-functionalized β …

[Reginato, Gianna; Mordini, Alessandro; Caracciolo, Massimo Journal of Organic Chemistry, 1997 , vol. 62, # 18 p. 6187 - 6192]

More Articles...