Synthesis of 1??and 3??amino??5??t??butyl??1H??and??3H??v??triazolo [4, 5??d] pyrimidines as hetaryne precursors

M Tielemans, D Christophe…

Index: Tielemans, Michel; Christophe, Daniel; Promel, Robert Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 705 - 708

Full Text: HTML

Citation Number: 6

Abstract

Abstract The synthesis of the title compounds 6 and 8 has first been accomplished by reaction of O-mesitylsulfonyl-hydroxylamine with 5-t-butyl-3H-v-triazolo [4, 5-d] pyrimidine (5) whose preparation is reported in detail. However the preferred route for the synthesis of the 3-amino derivative 8 is based upon the preparation of 3-benzylideneamino-5-t-butyl-3H- v-triazolo [4, 5-d] pyrimidine (10), followed by the removal of the benzylidene protecting ...