Tetrahedron letters

Radical-mediated bromination of carbohydrate derivatives: searching for alternative reaction conditions without carbon tetrachloride

K Czifrák, L Somsák

Index: Czifrak, Katalin; Somsak, Laszlo Tetrahedron Letters, 2002 , vol. 43, # 49 p. 8849 - 8852

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Citation Number: 12

Abstract

KBrO3–Na2S2O4 in CH2Cl2–H2O or PhCF3–H2O biphasic solvent systems was applied to the bromination of several monosaccharide derivatives having capto-datively substituted reaction centres. With less reactive compounds neat PhCF3 was shown to be a suitable substitute of the health and environmentally hazardous carbon tetrachloride.