Tetrahedron: Asymmetry

Preparation of quarternary ammonium salt-tagged ferrocenylphosphine-imine ligands and their application to palladium-catalyzed asymmetric allylic substitution

H Yuan, Z Zhou, J Xiao, L Liang, L Dai

Index: Yuan, Hao; Zhou, Zhiming; Xiao, Jiangliang; Liang, Lixuan; Dai, Li Tetrahedron Asymmetry, 2010 , vol. 21, # 15 p. 1874 - 1884

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Citation Number: 15

Abstract

A series of novel quarternary ammonium salt-modified chiral ferrocenylphosphine-imine ligands have been synthesized and the molecular structure of BIT5 has been determined by single-crystal X-ray diffraction. The applicability of these ligands in asymmetric C∗–C and C∗–N bond formation was demonstrated. High enantioselectivity was obtained in the Pd- catalyzed asymmetric substitution of 1, 3-diphenyl-2-propenyl acetate, with dimethyl ...