Triamides prepared by the diacylation of amides

RT LaLonde, CB Davis

Index: LaLonde,R.T.; Davis,C.B. Journal of Organic Chemistry, 1970 , vol. 35, p. 771 - 774

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Citation Number: 9

Abstract

Nine new aliphatic and or,@-unsaturated triamides were prepared from acyl chlorides and amides in the presence of pyridine or or-substituted pyridines. Factors which affect the extent of amide acylation are (1) the sequence of reactant and pyridine mixing;(2) temperature; and (3) substitution at the 01 positions of both acyl chloride and the pyridine.