Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen) CoIII complexes. Practical synthesis of enantioenriched terminal epoxides …

SE Schaus, BD Brandes, JF Larrow…

Index: Wyatt, Peter B.; Blakskjaer, Peter Tetrahedron Letters, 1999 , vol. 40, # 35 p. 6481 - 6483

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Citation Number: 894

Abstract

... Therefore, if HKR did not afford epoxide in >99% ee with catalyst prepared by method B after optimization of solvent and catalyst loading, then catalyst prepared by method A was ... In general, one volume of solvent relative to racemic epoxides was sufficient to allow efficient HKR. ...