Cerium (IV) ammonium nitrate mediated nitration of coumarins

N Ganguly, AK Sukai, S De

Index: Ganguly; Sukai; De Synthetic Communications, 2001 , vol. 31, # 2 p. 301 - 309

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Citation Number: 20

Abstract

A new convenient method of nitration of coumarins using cerium (IV) ammonium nitrate (CAN) has been developed. Higher regioselectivity is observed with CAN and hydrogen peroxide in aqueous medium in comparison with CAN in acetic acid for nitration of 7- hydroxycoumarin, 7-hydroxy-4-methyl coumarin and their derivatives.