The Aldol Reaction under High??Intensity Ultrasound: A Novel Approach to an Old Reaction

…, G Palmisano, A Penoni, S Tagliapietra

Index: Cravotto, Giancarlo; Demetri, Alberto; Nano, Gian Mario; Palmisano, Giovanni; Penoni, Andrea; Tagliapietra, Silvia European Journal of Organic Chemistry, 2003 , # 22 p. 4438 - 4444

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Citation Number: 45

Abstract

Abstract We have employed high-intensity ultrasound (HIU) to reinvestigate the aldol reaction (AR) in water. A number of aldols that under usual conditions would undergo elimination were isolated in acceptable to good yields. Within 15− 30 min, acetophenone reacted with non-enolizable aldehydes to afford the aldol exclusively, while under conventional conditions (stirring or heating under reflux) the same compounds either ...

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