Synthesis and Local Anesthetic Activity of ortho-(Cyclopentenyl)-and ortho-(Cyclopentyl)-aniline Derivatives

…, TV Kazhanova, LT Karachurina, LT Il'yasova…

Index: Gataullin; Kazhanova; Karachurina; Il'yasova; Davydova; Sapozhnikova; Zarudii; Abdrakhmanov Pharmaceutical Chemistry Journal, 2001 , vol. 35, # 9 p. 493 - 497

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Abstract

Recently [1, 2], we reported on the synthesis of compounds possessing local anesthetic and analgesic properties in the series of a-aminoacetyl derivatives of 2-pentenyl-and 2- cyclopentenylanilines. In continuation of the research in this direction, we have synthesized and characterized a series of a-aminoacetanilide hydrochlorides obtained from ortho- (cyclopent-1-and-2-enyl) anilines and cyclopentylanilines and N- ...

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