The Journal of Organic Chemistry

Transmetalation reactions of alkylzirconocenes: copper-catalyzed conjugate addition to enones

P Wipf, JH Smitrovich

Index: Wipf, Peter; Smitrovich, Jacqueline H. Journal of Organic Chemistry, 1991 , vol. 56, # 23 p. 6494 - 6496

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Citation Number: 67

Abstract

Summary: Rapid hydrozirconation of alkenes by zirconocene hydrochloride, followed by addition of 1 equiv of enone and catalytic amounts of Cu (1) salts, led to the corresponding 1, Caddition products in moderate to high yields and provided the first protocol for in situ preparation of alkyl cuprates from alkenes.

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