Indole as a dienophile in inverse electron demand Diels-Alder reactions: reactions with 1, 2, 4-triazines and 1, 2-diazines

SC Benson, JL Gross, JK Snyder

Index: Benson, Scott C.; Gross, Jonathan L.; Snyder, John K. Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3257 - 3269

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Citation Number: 76

Abstract

The inverse electron demand Diels-Alder cycloaddition employing azadienes has become an important tool for the synthesis of biologically active natural'and unnatural* product^.^ Though the use of indole as a dienophile in both inverse4 and normal5 electron demand cycloadditions has been limited, the number of examples is increasing. We recently reported that indole and several of its simple derivatives undergo a facile inverse electron demand ...