Journal of the American Chemical Society

An enantiodirected cyclopentenone annulation. Synthesis of a useful building block for condensed cyclopentanoid natural products

BM Trost, DP Curran

Index: Trost; Curran Journal of the American Chemical Society, 1980 , vol. 102, # 17 p. 5699 - 5700

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Citation Number: 115

Abstract

(Ph, P), Pd (5%), DBU, THF, 66" C, H, O (2 equiv), Me, SO, 15-25" C. 12 h. aqueous K, CO,. e 40" C. of this route for asymmetric synthesis, an important feature for the synthesis of natural products. Previous methods of cyclopentenone annulati~ n~~,~ have generally not been used for the synthesis of bicyclo [3.3. 0] compounds, and most are not applicable to the synthesis of 2 because of the known tendencies of 2, 2-disubstituted-1, 3- ...