Cation anion combination reactions. 20. Reactions of nucleophiles with trans-3-methoxy-and trans-3-(methylthio) acrylophenones

CD Ritchie, A Kawasaki

Index: Ritchie, Calvin D.; Kawasaki, Atsushi Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4704 - 4708

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Citation Number: 4

Abstract

The reactions of a number of nucleophiles with trans-3-methoxyacrylophenone (MeOAcr) and with trans-3-(methylthio) acrylophenone (MeSAcr) in water and methanol have been studied. The reactions of amines produce enamines as the first observable products, and primary amines show simple kinetics: first-order with respect to amine and first-order with respect to the acrylophenone. Piperidine reactions show kinetics which are consistent with ...