Synlett

Microwave-assisted copper-catalyzed Heck reaction in PEG solvent

V Declerck, J Martinez, F Lamaty

Index: Declerck, Valerie; Martinez, Jean; Lamaty, Frederic Synlett, 2006 , # 18 p. 3029 - 3032

Full Text: HTML

Citation Number: 26

Abstract

Abstract A catalytic system made of a copper salt, potassium carbonate and PEG 3400 was developed to perform a Heck arylation under microwave activation. Copper iodide gave the best results in a short reaction time (30 min) and various substituted tert-butyl cinnamates could be synthesized. Better results were usually obtained after recycling the catalyst/solvent system.

Related Articles:

A new version of the Peterson olefination using bis (trimethylsilyl) methyl derivatives and fluoride ion as catalyst

[Palomo, Claudio; Aizpurua, Jesus M.; Garcia, Jesus M.; Ganboa, Inaki; Cossio, F. P.; et al. Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2498 - 2503]

Controlled mono and double Heck reactions in water catalyzed by an oxime-derived palladacycle

[Botella, Luis; Najera, Carmen Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1833 - 1836]

Mono-and β, β-double-Heck reactions of α, β-unsaturated carbonyl compounds in aqueous media

[Botella, Luis; Najera, Carmen Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4360 - 4369]

β-Elimination of the isonitrile group in alkylation reactions of C–H acids activated by the isonitrile function

[Jawdosiuk, Mikolaj; Uminski, Maciej Journal of the Chemical Society, Chemical Communications, 1982 , # 17 p. 979 - 980]

More Articles...