Synthesis and biological properties of N-(ω-aminoalkyl)-substituted 2-pyrrolidones and their derivatives

…, IV Lizak, LK Kulikova, EE Ostroumova

Index: Sedavkina, V. A.; Lizak, I. V.; Kulikova, L. K.; Ostroumova, E. E. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 1 p. 37 - 40 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 1 p. 54 - 58

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Citation Number: 9

Abstract

Using the first two catalysts, the reaction proceeds with heating at 80-I00~ and a hydrogen pressure of 100-120 atm, but with the ruthenium catalyst it occurs at ambient temperature. The yields of the required products using the ruthenium catalyst were 20-25% greater than when the nickel catalysts were used.