A short and efficient synthesis of (R)-(−)-sporochnol A

…, F Busqué, GG Bardají, P de March, M Figueredo…

Index: Alibes, Ramon; Busque, Felix; Bardaji, Gisela G.; de March, Pedro; Figueredo, Marta; Font, Josep Tetrahedron Asymmetry, 2006 , vol. 17, # 18 p. 2632 - 2636

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Citation Number: 6

Abstract

A short and efficient synthesis of (R)-(−)-sporochnol A in five steps and 9% overall yield has been developed. The sequence uses as starting material the easily available enantiopure monoketal derived from 1, 4-cyclohexanedione and (R, R)-hydrobenzoin that serves as a chiral auxiliary.