Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists
J Cheng, JD McCorvy, PM Giguere, H Zhu…
Index: Buccini, Marco; Piggott, Matthew J. Organic Letters, 2014 , vol. 16, # 9 p. 2490 - 2493
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Abstract
... J. Med. ... In our previous work, we identified compounds 3 and 4 as highly selective 5-HT 2C agonists (Figure 1).(9, 10) Both ... of fact, both benzofuran and 2,3-dihydrobenzofuran have been reported as substructures of 5-HT 2A/2C receptor ligands previously.(16) We anticipated ...
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