One-pot synthesis of aziridines from vinyl selenones and variously functionalized primary amines

…, F Del Verme, A Calandriello, L Testaferri, M Tiecco

Index: Sternativo, Silvia; Marini, Francesca; Del Verme, Francesca; Calandriello, Antonella; Testaferri, Lorenzo; Tiecco, Marcello Tetrahedron, 2010 , vol. 66, # 34 p. 6851 - 6857

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Citation Number: 24

Abstract

Variously substituted aziridines were conveniently prepared by an aza-Michael Initiated Ring Closure (aza-MIRC) reaction starting from vinyl selenones and primary amines, aminoalcohols or diamines. The reactions proceed in very high yields at room temperature in toluene or water. A significant rate acceleration was observed under aqueous conditions.