Tetrahedron letters

Preparation of α, β-dehydro-β-amino acid derivatives by tin-promoted addition of malonates to simple nitriles

F Scavo, P Helquist

Index: Scavo, Frank; Helquist, Paul Tetrahedron Letters, 1985 , vol. 26, # 22 p. 2603 - 2606

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Citation Number: 23

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Simple aliphatic and aromatic nitriles undergo reaction with malonate esters in the presence of tin(IV) chloride to give derivatives of α,β-dehydro-β-amino acids. The same products are obtained through use of bromomalonate esters. ... Cookies are used by this site. To decline or ...