Asymmetric Cycloaddition Reactions of Diazoesters with 2-Alkenoic Acid Derivatives Catalyzed by Binaphthyldiimine–Ni (II) complexes

…, T Tsuchida, A Kakehi, T Baba

Index: Suga, Hiroyuki; Adachi, Yuki; Fujimoto, Kouhei; Furihata, Yasuhisa; Tsuchida, Teruko; Kakehi, Akikazu; Baba, Toshihide Journal of Organic Chemistry, 2009 , vol. 74, # 3 p. 1099 - 1113

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Citation Number: 24

Abstract

The catalytic activity of chiral binaphthyldiimine (BINIM)–Ni (II) complexes for asymmetric enantioselective diazoalkane cycloadditions of ethyl diazoacetate with 3-acryloyl-2- oxazolidinone and 2-(2-alkenoyl)-3-pyrazolidinone derivatives was evaluated. The cycloadditions of 3-acryloyl-2-oxazolidinone and its 5, 5-dimethyl derivative, in the presence of the BINIM–Ni (II) complex (10 mol%; prepared from (R)-BINIM-4Ph-2QN (ligand C) and ...