INDOLPhos: novel hybrid phosphine-phosphoramidite ligands for asymmetric hydrogenation and hydroformylation

J Wassenaar, JNH Reek

Index: Wassenaar, Jeroen; Reek, Joost N. H. Dalton Transactions, 2007 , # 34 p. 3750 - 3753

Full Text: HTML

Citation Number: 27

Abstract

Enantioselective transition metal catalysis has emerged as a unique tool for the introduction of chirality in pharmaceuticals and fine chemical intermediates. Asymmetric catalytic hydrogenation has become particular important as many different building blocks with a variety of functional groups becomes accessible. 1 Traditionally, chiral bidentate phosphine ligands 2 have dominated this field until more recently Feringa and De Vries, 3 Reetz 4 and Pringle 5 introduced the ...