Synlett

Oxidative kinetic resolution of alkyl aryl sulfoxides

I Mohammadpoor-Baltork, M Hill, L Caggiano…

Index: Mohammadpoor-Baltork, Iraj; Hill, Mathias; Caggiano, Lorenzo; Jackson, Richard F. W. Synlett, 2006 , # 20 p. 3540 - 3544

Full Text: HTML

Citation Number: 18

Abstract

Abstract Kinetic resolution is observed in the oxidation of racemic alkyl aryl sulfoxides using a combination of VO (acac) 2 and ligand 1 in chloroform at 0 C, conditions previously described for asymmetric oxidation of prochiral sulfides. Kinetic resolution is also observed in toluene as the solvent, although higher temperatures are required.

Related Articles:

A mild and efficient new synthesis of aryl sulfones from boronic acids and sulfinic acid salts

[Beaulieu, Christian; Guay, Daniel; Wang, Zhaoyin; Evans, David A. Tetrahedron Letters, 2004 , vol. 45, # 16 p. 3233 - 3236]

An improved high yielding immobilization of vanadium Schiff base complexes on mesoporous silica via azide–alkyne cycloaddition for the oxidation of sulfides

[Jain, Suman L.; Rana, Bharat S.; Singh, Bhawan; Sinha, Anil K.; Bhaumik, Asim; Nandi, Mahasweta; Sain, Bir Green Chemistry, 2010 , vol. 12, # 3 p. 374 - 377]

Preparation of enantiopure 2, 2, 5, 5-tetramethyl-3, 4-hexanediol and its use in catalytic enantioselective oxidation of sulfides to sulfoxides

[Yamanoi, Yoshinori; Imamoto, Tsuneo Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8560 - 8564]

2-(4-Pyridyl) ethyl as a protective group for sulfur functionality

[Katritzky, Alan R.; Takahashi, Ichiro; Marson, Charles M. Journal of Organic Chemistry, 1986 , vol. 51, # 25 p. 4914 - 4920]

2-(4-Pyridyl) ethyl as a protective group for sulfur functionality

[Katritzky, Alan R.; Takahashi, Ichiro; Marson, Charles M. Journal of Organic Chemistry, 1986 , vol. 51, # 25 p. 4914 - 4920]

More Articles...