Tetrahedron Letters

A simple and efficient synthesis of N-benzoyl ureas

S Stokes, NG Martin

Index: Stokes, Stephen; Martin, Nathaniel G. Tetrahedron Letters, 2012 , vol. 53, # 36 p. 4802 - 4804

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Citation Number: 3

Abstract

The N-benzoyl urea moiety is an important functional group in the fields of both medicinal chemistry 1 and agrochemicals. 2 Moreover, a number of N-benzoyl ureas show promising anti-tumour properties 3 and some have found commercial use in agriculture as insecticides. 4 As part of an ongoing research programme, we sought a mild and efficient route to this class of acyl ureas. ... N-Acyl ureas are classically prepared by reaction of N-acylisocyanates with ...

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