Syntheses and reactions of some 2, 3??disubstituted pyrazine monoxides

…, Y Akita, T Watanabe, T Kurihara

Index: Watahiki, Hiroko; Tsutsui, Mayumi; Akita, Yasuo; Watanabe, Tokuhiro; Kurihara, Teruo Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 465 - 473

Full Text: HTML

Citation Number: 27

Abstract

Abstract The reactions of 2, 3-dimethyl-(4), 2, 3-diphenyl-(6), and 2-methyl-3-phenyl- pyrazine monoxides (8 and 9) with phosphoryl chloride and acetic anhydride resulted in giving monochloro-and monacetoxy-pyrazines in almost all cases. However, the reaction of 6 with acetic anhydride afforded exceptionally a diacetoxydihydro-pyrazine. These products were converted further to hydroxy or dichloro derivatives.