Bioorganic & medicinal chemistry

Synthesis of [14, 14, 14-2 H 3] 12-hydroxytetradecanoic acid and [13, 14-2 H 2] 11-hydroxytetradecanoic acid useful as tracers to study a (11E)-desaturation reaction …

I Navarro, G Fabriás, F Camps

Index: Navarro; Fabrias; Camps Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 3 p. 439 - 443

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Citation Number: 5

Abstract

The synthesis of deuterium labeled 11-and 12-hydroxytetradecanoic acids to study a (11E) desaturase in the moth Spodoptera littoralis is reported.[14, 14, 14-2H3] 12- hydroxytetradecanoic acid was synthesized in four steps from 11-iodo-1-undecene in 49%

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