Cascade Synthesis of Polyoxygenated 6 H, 11 H-[2] Benzopyrano-[4, 3-c][1] benzopyran-11-ones

…, V Bourgarel-Rey, S Combes, JP Finet…

Index: Naumov, Mikael I.; Sutirin, Sergey A.; Shavyrin, Andrey S.; Ganina, Olga G.; Beletskaya, Irina P.; Bourgarel-Rey, Veronique; Combes, Sebastien; Finet, Jean-Pierre; Fedorov, Alexey Yu. Journal of Organic Chemistry, 2007 , vol. 72, # 9 p. 3293 - 3301

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Citation Number: 19

Abstract

2-(Methoxymethoxymethyl) aryllead triacetates, obtained in situ from the corresponding arylboronic acids, reacted with 4-hydroxycoumarins, leading to 3-(2-methoxymethoxymethyl) aryl-4-hydroxycoumarin derivatives in good to high yields. These compounds underwent a cascade sequence of reactions, deprotection-halogenation-annulation, to afford polyoxygenated tetracyclic 6 H, 11 H-[2] benzopyrano-[4, 3-c][1] benzopyran-11-ones in ...