ZnO as a new catalyst for N-formylation of amines under solvent-free conditions

M Hosseini-Sarvari, H Sharghi

Index: Hosseini-Sarvari, Mona; Sharghi, Hashem Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6652 - 6654

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Citation Number: 198

Abstract

The treatment of amines with formic acid in the presence of ZnO under solvent-free conditions brings about highly and efficient N-formylation to give the corresponding formamides in excellent yields. The N-formylation reaction not only involves mild conditions, simple operation, and high yields but also high chemoselectivity.