Synthesis and antioxidant properties of substituted 2-phenyl-1H-indoles

C Karaaslan, H Kadri, T Coban, S Suzen…

Index: Karaaslan, Cigdem; Kadri, Hachemi; Coban, Tulay; Suzen, Sibel; Westwell, Andrew D. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2671 - 2674

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Citation Number: 10

Abstract

In this study, we report the design, synthesis and antioxidant activity of a series of substituted 2-(4-aminophenyl)-1H-indoles and 2-(methoxyphenyl)-1H-indoles. The new compounds are structurally related to the known indole-based antioxidant lead compound melatonin (MLT), and the antitumour 2-(4-aminophenyl) benzothiazole and 2-(3, 4-dimethoxyphenyl) benzothiazole series. Efficient access to the target 2-phenylindoles was achieved via ...