Conversion of alkyl carbamates into amines via treatment with trimethylsilyl iodide

ME Jung, MA Lyster

Index: Jung,M.E.; Lyster,M.A. Journal of the Chemical Society, Chemical Communications, 1978 , p. 315 - 316

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Citation Number: 63

Abstract

THE carbamate functionality is a useful and common protecting group for primary and secondary amines. While many specific carbamates have been developed for their ease of conversion back into the amines under mild con- ditions,' the simple, more easily obtainable alkyl carba- mates have not been often employed because of the harsh conditions usually necessary.g s 3 Two exceptions to this are benzyl carbamates,' which can be converted into the amines