Journal of Heterocyclic Chemistry

Synthesis of certain metabolites and analogs of vitamin B6 and their ring??chain tautomerism

B Paul, W Korytnyk

Index: Paul,B.; Korytnyk,W. Journal of Heterocyclic Chemistry, 1976 , vol. 13, p. 701 - 709

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Citation Number: 3

Abstract

Abstract Pyridoxol and pyridoxal on benzylation with dimethylphenylbenzylammonium hydroxide (“leucotrope”) gave 3-O-benzylpyridoxol (IV) and 3-O-benzylpyridoxal (V), respectively. As a possible mechanism of this reaction an ion pair intermediate has been postulated. Oxidation of IV and V with chromic oxide-pyridine-acetic acid complex gave 3-O- benzyl-4-pyridoxic acid lactone (VI), which could also be obtained by benzylation of 4- ...