Synthetic Communications

A General Method for the Preparation of 6-Hydroxy-4-Alkyl-Hexanals

F Kienzle

Index: Kienzle,F. Synthetic Communications, 1976 , vol. 6, p. 465 - 468

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Citation Number: 2

Abstract

Abstract 6-Hydroxy-4-alkylhexanals are important intermediates in the synthesis of juvenile hormones and their analogs. We wish to report an economic route to these compounds which starts essentially with an easily accessible p-substituted phenol. Catalytic hydrogenation of the phenol is known 1 to give, depending on the reaction conditions, either the corresponding cyclohexanone or the cyclohexanol. The latter is easily oxidized to the ...