Inhibitors of acyl CoA: cholesterol acyltransferase

W Vaccaro, C Amore, J Berger, R Burrier…

Index: Journal of Medicinal Chemistry, , vol. 39, # 8 p. 1704 - 1719

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Citation Number: 49

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The requisite 2-aryl ketones 8−11 were prepared as depicted in Scheme 1. In method 1, conversion of 12 to the enol acetate 13 followed by palladium-mediated arylation 4 provided ketones 9 and 10. ...