Tetrahedron

An efficient synthesis of quinazoline-2, 4-dione derivatives with the aid of a low-valent titanium reagent

DQ Shi, GL Dou, ZY Li, SN Ni, XY Li, XS Wang, H Wu…

Index: Shi, Da-Qing; Dou, Guo-Lan; Li, Zheng-Yi; Ni, Sai-Nan; Li, Xiao-Yue; Wang, Xiang-Shan; Wu, Hui; Ji, Shun-Jun Tetrahedron, 2007 , vol. 63, # 39 p. 9764 - 9773

Full Text: HTML

Citation Number: 44

Abstract

Low-valent titanium reagents have exceedingly high ability to promote reductive coupling of carbonyl compounds and are attracting increasing interest in organic synthesis. 1, 1a, 1b, 1c, 1d, 1e and 1f Recently, we have reported the cyclodimerization of α,β-unsaturated ketones and α,β-unsaturated nitriles promoted by this reagent yielding functional cyclopentanes 2 and cyclopentenes, 3 respectively. ... Over the past decade, the synthesis of heterocycles has ...

Related Articles:

Rearrangement of 4-imino-(1H, 4H)-3, 1-benzoxazine-2-ones to 2, 4-quinazolinediones via an isocyanate carboxamide intermediate

[Azizian, Javad; Mehrdad, Morteza; Jadidi, Khosrow; Sarrafi, Yaghob Tetrahedron Letters, 2000 , vol. 41, # 27 p. 5265 - 5268]

An efficient one-pot procedure for preparation of 2, 4 (1 H, 3 H)-quinazolinediones and 2-thioxoquinazolinone derivatives under microwave irradiation

[Azizian, Javad; Mohammadi, Ali A.; Karimi, Ali R. Synthetic Communications, 2003 , vol. 33, # 3 p. 415 - 420]

Palladium-catalyzed cyclocarbonylation of o-iodoanilines with heterocumulenes: regioselective preparation of 4 (3 H)-quinazolinone derivatives

[Larksarp, Chitchamai; Alper, Howard Journal of Organic Chemistry, 2000 , vol. 65, # 9 p. 2773 - 2777]

More Articles...