Oxidative demethylation in monooxygenase model systems. Competing pathways for binuclear and helical multinuclear copper (I) complexes

OJ Gelling, BL Feringa

Index: Gelling; Feringa Journal of the American Chemical Society, 1990 , vol. 112, # 21 p. 7599 - 7604

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Citation Number: 61

Abstract

The complexes mimic certain monooxygenases as they rapidly take up O2 followed by demethylation of the anisole moiety (up to 95% yield)." 0 experiments are provided that show competing aryl-oxygen (160%) and alkyl-oxygen (20%) bond cleavage pathways. Introduction of a p-methoxy substituent in the arene moiety of complex 11 decreases the oxygenation rate and led to an unprecedented O2 induced arene-OCH3-OCD, exchange ...