Tetrahedron letters

A novel method for cyclopentanone annulation. The use of 1-(2-ketoalkyl) cyclopropanols to obtain cyclopentanones.

JT Carey, P Helquist

Index: Carey, James T.; Helquist, Paul Tetrahedron Letters, 1988 , vol. 29, # 11 p. 1243 - 1246

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Citation Number: 13

Abstract

Abstract The condensation of alkyl-substituted thermodynamic enolates with ethyl bromomagnesium cyclopropanone hemiacetal (a cyclopropanone equivalent) provides 1-(2- ketoalkyl) cyclopropanols which in turn are converted into 3-hydroxycyclopentanones by treatment with base.

Metal-Free Difunctionalization of Alkynes with 2-Chlorodithiane for Synthesis of β-Ketodithianes

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Intramolecular hydride shift in some noncyclic isopropyl ketols

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α??Aminosäuren als nucleophile Acyläquivalente, II. Synthese von γ??Diketonen unter Verwendung von Oxazolin??5??onen

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