Aromatic fluoroalkoxylation via direct aromatic nucleophilic substitution
…, JT Gupton, CK McCurry, AD Crews…
Index: Idoux, John P.; Gupton, John T.; McCurry, Cynthia K.; Crews, A. Donald; Jurss, Cindy D.; et al. Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3771 - 3773
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Citation Number: 43
Abstract
The reaction of activated aryl and heteroaryl halides with fluorinated alkoxide anions is described. In all cases, substitution of the halogen by a fluoroalkoxy group was observed. The effect of solvent, time, temperature, the activating group, leaving group, and the nucleophile on this reaction is also discussed.
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