Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents

M Flipo, T Beghyn, V Leroux, I Florent…

Index: Sicker, D.; Rabe, A.; Zakrzewski, A.; Mann, G. Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 6 p. 1063 - 1070

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Citation Number: 51

Abstract

... Journal ... range of % inhibition at 10 μM. series of amines, <50%, [50−80%], >80%. A, 54, 13, 33. B, 77, 13, 10. C, 44, 28, 28. D, 60, 20, 20. E, 73, 27, 0. F, 81, 11, 8. G, 65, 24, 11. Table 3. Inhibition of PfA-M1 by iso-Butyl Compounds 32−41. a Mean of two experiments. SD was <10% ...