Helvetica chimica acta

A simple and effective chemical phosphorylation procedure for biomolecules

W Bannwarth, A Trzeciak

Index: Bannwarth, Willi; Trzeciak, Arnold Helvetica Chimica Acta, 1987 , vol. 70, p. 175 - 186

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Citation Number: 271

Abstract

Abstract A general chemical phosphorylation method based on P (III) chemistry has been developed. The system is demonstrated for the phosphorylation of oligonucleotides, directly after their synthesis on a solid support, and for the O-phosphorylation of serine, threonine, and tyrosine as well as for a serine-containing peptide.

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