Transmission of polar substituent effects in bicycloalkane systems. Synthesis and nuclear magnetic resonance study (carbon-13 and fluorine-19) of 4-substituted …

W Adcock, AN Abeywickrema…

Index: Adcock, William; Abeywickrema, Anil N.; Kok, Gaik B. Journal of Organic Chemistry, 1984 , vol. 49, p. 1387 - 1397

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Citation Number: 38

Abstract

A number of 4-substituted (X) bicyclo [2.2. l] hept-l-y1 fluorides (2) have been synthesized, and their 13C and l9F NMR spectra have been recorded. The synthesis of all these compounds, except for the parent (2, X= H) of the series, has been accomplished from 4- fluorobicyclo [2.2. 1] heptane-l-carboxylic acid (2, X= COOH) by, in the main, functionalization procedures previously employed for the synthesis of 4-substituted (X) ...