A novel synthetic route to (±)-perhydrogephyrotoxin

T Ibuka, GN Chu, F Yoneda

Index: Ibuka, Toshiro; Chu, G.-Namg; Yoneda, Fumio Journal of the Chemical Society, Chemical Communications, 1984 ,  # 9  p. 597 - 599

Full Text: HTML

Citation Number: 0

Abstract

Toshiro lbuka,* G.-Namg Chu, and Fumio Yoneda Faculty of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606, Japan ... Total synthesis of (+)-perhydrogephyrotoxin (3) starting from 1,3-bis(trimethylsiloxy)buta-l,3-diene is presented; an efficient new decarboxylative reduction of y-carbamoyloxy-a,(3-enoate (14) by lithium dibutylcuprate is also presented. ... The structures of gephyrotoxin (1) and dihydrogephyrotoxin (2), isolated from the skin extract of the ...