Synthesis

Photosensitized Oxidation of Furans; Part 17: A Simple Method for the Synthesis of 5-Hydroperoxyfuran-2 (5H)-ones

MR Iesce, F Cermola, ML Graziano, R Scarpati

Index: Iesce; Cermola; Graziano; Scarpati Synthesis, 1994 ,  # 9  p. 944 - 948

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Citation Number: 16

Abstract

The 5-hydroperoxyfuran-2 (5H)-ones 3 are synthesized by acid hydrolysis of the dihydrofurans 1 which are prepared in one-pot procedure by reaction of the corresponding furans 4 with singlet oxygen and methanol. The synthetic method has a wide range of applicability; however, compounds 3 unsubstituted at C-4 cannot be prepared since the corresponding dihydrofurans 1 are not formed. The furan-2 (5H)-one skeleton appears in ...