Direct cleavage versus transpeptidation in the autodecomposition of peptides containing 2, 4-diaminobutanoic acid (DABA) and 2, 3-diaminopropanoic acid (DAPA) …

JK Blodgett, GM Loudon

Index: Blodgett, James K.; Loudon, G. Marc Journal of the American Chemical Society, 1989 ,  vol. 111,  # 17  p. 6813 - 6821

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Citation Number: 10

Abstract

Abstract: Peptides containing 2, 4-diaminobutanoic acid and 2, 3-diaminopropanoic acid residues undergo transpeptidation by attack of their side-chain amino groups on the N- carbonyl (eq 2). Little or no direct cleavage by attack on the C-carbonyl (eq 1) is observed. The transpeptidation reactions of peptides containing 2, 4-diaminobutanoic acid (DABA) or 2, 3-diaminopropanoic acid (DAPA) residues reach an equilibrium in which the various ...