Indium-mediated allylation of acyl cyanides in aqueous media: A convenient synthesis of β, γ-unsaturated ketones

…, KH Choi, SJ Lee, GS Nam, KY Chang…

Index: Yoo, Byung Woo; Choi, Kwang Hyun; Lee, Sung Jae; Nam, Ghil Soo; Chang, Kwan Young; Kim, Sung Hoon; Kim, Joong Hyup Synthetic Communications, 2002 , vol. 32, # 6 p. 839 - 846

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Citation Number: 10

Abstract

View all references However, these reactions are of limited application, not being very simple and straightforward. We have found that acyl cyanide can act as an electrophile in the indium-mediated allylation in aqueous media to achieve carbon–carbon bond formation. To the best of our knowledge, the indium-mediated allylation has never been applied to acyl cyanides as activated carboxylic acid derivative. In our methodology synthesizing β,γ-unsaturated ...

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